China wholesale Eucalyptus Oil - Natural Coumarin Osthole from Medicinal Plants – SENTON
China wholesale Eucalyptus Oil - Natural Coumarin Osthole from Medicinal Plants – SENTON Detail:
| Product Name | Osthole |
| CAS No. | 484-12-8 |
| MF | C15H16O3 |
| MW | 244.290 g·mol−1 |
| Boiling point | 396.7℃ |
| Melting point | 82.0-86℃ |
| Packaging: | 25KG/Drum, or as Custimised requirement |
| Productivity: | 1000 tons/ year |
| Brand: | SENTON |
| Transportation: | Ocean,Air，Land |
| Place of Origin: | China |
| Certificate: | ISO9001，FDA |
| HS Code: | 29335990.13 |
| Port: | Shanghai,Qingdao,Tianjin |
Product Description
Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens.1 It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.
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