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Hot-selling Alliin Allicin - Natural Coumarin Osthole from Medicinal Plants – SENTON

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Hot-selling Alliin Allicin - Natural Coumarin Osthole from Medicinal Plants – SENTON Detail:

Product Name Osthole
CAS No. 484-12-8
MF C15H16O3
MW 244.290 g·mol−1
Boiling point 396.7
Melting point  82.0-86

 

Packaging:  25KG/Drum, or as Custimised requirement
Productivity:  1000 tons/ year
Brand:  SENTON
Transportation:  Ocean,Air,Land
Place of Origin:  China
Certificate:  ISO9001,FDA
HS Code: 29335990.13
 Port:  Shanghai,Qingdao,Tianjin

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Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens.1 It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

Leads to Modulation of Calcium

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