Veterinary Antibiotics Medicine Raw Soluble Powder 99% Nuflor Florfenicol CAS 73231-34-2
Product | Florfenicol |
CAS | 73231-34-2 |
Appearance | White or white powder |
Florfenicol is a commonly used veterinary antibiotic with a wide antibacterial spectrum, strong antibacterial effect, low minimum inhibitory concentration (MIC), high safety, non toxicity, and no residue. It has no potential risk of causing aplastic anemia and is suitable for large-scale breeding farms. It is mainly used to treat bovine respiratory diseases caused by Pasteurella and Haemophilus bacteria. It has a good therapeutic effect on bovine foot rot caused by Clostridium. It is also used for infectious diseases caused by sensitive bacteria in pigs and chickens, as well as bacterial diseases in fish.
Pharmacological action | The antibacterial spectrum and antibacterial activity of this product are slightly better than that of sulfoxamycin, and it has strong antibacterial activity against a variety of gram-positive bacteria, gram-negative bacteria and mycoplasma. Pasteurella hemolyticus, Pasteurella multocida, actinobacillus suis pleuritis are highly sensitive to this product, and are sensitive to streptococcus, sulfonicin-resistant Shigella dysentery, Salmonella typhi, Klebsiella, Escherichia coli and ampicillin resistant Haemophilus influenzae. Bacteria can develop acquired resistance to flufenicol, and show cross-resistance with thiamphenicol, but due to the inactivation of acetyltransferase, this product is still sensitive to it. It is mainly used for bacterial diseases of cattle, pigs, chickens and fish, such as bovine respiratory diseases caused by Pasteulosis and hemophilus, bovine infectious keratoconjunctivitis, porcine actinomycous pleuropneumonia, fish disease and so on. It can also be used to treat cow mastitis caused by various pathogens. Strong bactericidal power, a wide antibacterial spectrum (negative bacteria, positive bacteria, rhodosoma, coccidia, mycoplasma, etc.) to reduce the generation of drug resistance. After oral administration, it quickly penetrates the intestinal wall through systemic circulation to reach the target tissue, reaching the peak blood concentration within 1-1.5 hours, the elimination half-life is as long as 17 hours, and the effective blood concentration can be maintained for 40-48 hours after a single administration. The bioavailability is as high as 95-100%, the drug concentration in lung tissue is 90% of the blood drug concentration, and the drug concentration in tracheal cavity and alveoli is higher than the blood drug concentration. |
attention | (1) The laying period of laying hens is prohibited. (2) Animals with renal insufficiency should reduce the dosage or extend the interval of administration. (3) Animals with severe immune function impairment or vaccination period are prohibited. |
Adverse reaction | (1) This product has hematological toxicity, although it does not cause irreversible bone marrow aplastic anemia, but it causes reversible inhibition of erythropoiesis more common. (2) This product has a strong immunosuppressive effect, about 6 times stronger . (3) Long-term internal administration can cause digestive disorder, vitamin deficiency or double infection symptoms. (4) It is toxic to embryos, and should be used with caution during pregnancy and lactation. |
Adaptive disorder | Respiratory diseases and mixed infections. Prevention and treatment of mycoplasma suis pneumonia, Haemophilus parasuis, infectious pleuropneumonia, pathogenic Escherichia coli, Streptococcus, Haemophilus suis (Eperythrozoon), Pasteurella, Salmonella, bordetella septica, mastitis, postpartum infection, etc. |
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